Can it be done yes but it wouldn't be easy and would take time. I'm not a ps user however my wife is a graphics art director and lives in it every day.

To do something like this and remove a fence you need to copy a surrounding area and pixel by pixel remove it. The areas of the sky, lighthouse and grass would be the easy parts. The buildings would be the hard part.

I'm also looking at this from a do you want a nice photo or one that looks ps? Doing good work would take time.